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Pharmacol 105 QuijanoC.AlvarezB.GattiR

Although amifostine was approved for clinical use 20 years ago, its side effects such as hypotension (125), gastrointestinal reactions like nausea and vomiting, and allergic reactions (126) have restricted its use in clinical practice (127)

As for parameter settings in the current analysis, the number of factors of unwanted variation estimated was 2 (k=2), and all genes in the normalized data set were used as control genes (default setting for control genes)

doi: 10.1093/ajcn/nqy223 73

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